Phenotypic modulation of smooth muscle cells in lymphoedema.
Identifieur interne : 001995 ( Main/Exploration ); précédent : 001994; suivant : 001996Phenotypic modulation of smooth muscle cells in lymphoedema.
Auteurs : F. Ogata [Japon] ; K. Fujiu [Japon] ; I. Koshima [Japon] ; R. Nagai [Japon] ; I. Manabe [Japon]Source :
- The British journal of dermatology [ 1365-2133 ] ; 2015.
Descripteurs français
- KwdFr :
- Actines (métabolisme), Adulte, Adulte d'âge moyen, Chaînes lourdes de myosine (métabolisme), Femelle, Fibrose (anatomopathologie), Humains, Immunohistochimie, Lymphoedème (anatomopathologie), Lymphoedème (métabolisme), Maladie chronique, Microscopie électronique à transmission, Myocytes du muscle lisse (métabolisme), Myocytes du muscle lisse (physiologie), Myosines du muscle lisse (métabolisme), Mâle, Phénotype, Sujet âgé, Sujet âgé de 80 ans ou plus, Vaisseaux lymphatiques (anatomopathologie), Vaisseaux lymphatiques (métabolisme).
- MESH :
- anatomopathologie : Fibrose, Lymphoedème, Vaisseaux lymphatiques.
- métabolisme : Actines, Chaînes lourdes de myosine, Lymphoedème, Myocytes du muscle lisse, Myosines du muscle lisse, Vaisseaux lymphatiques.
- physiologie : Myocytes du muscle lisse.
- Adulte, Adulte d'âge moyen, Femelle, Humains, Immunohistochimie, Maladie chronique, Microscopie électronique à transmission, Mâle, Phénotype, Sujet âgé, Sujet âgé de 80 ans ou plus.
English descriptors
- KwdEn :
- Actins (metabolism), Adult, Aged, Aged, 80 and over, Chronic Disease, Female, Fibrosis (pathology), Humans, Immunohistochemistry, Lymphatic Vessels (metabolism), Lymphatic Vessels (pathology), Lymphedema (metabolism), Lymphedema (pathology), Male, Microscopy, Electron, Transmission, Middle Aged, Myocytes, Smooth Muscle (metabolism), Myocytes, Smooth Muscle (physiology), Myosin Heavy Chains (metabolism), Phenotype, Smooth Muscle Myosins (metabolism).
- MESH :
- chemical , metabolism : Actins, Myosin Heavy Chains, Smooth Muscle Myosins.
- metabolism : Lymphatic Vessels, Lymphedema, Myocytes, Smooth Muscle.
- pathology : Fibrosis, Lymphatic Vessels, Lymphedema.
- physiology : Myocytes, Smooth Muscle.
- Adult, Aged, Aged, 80 and over, Chronic Disease, Female, Humans, Immunohistochemistry, Male, Microscopy, Electron, Transmission, Middle Aged, Phenotype.
Abstract
Lymphoedema is a debilitating progressive condition that is frequently observed following cancer surgery and severely restricts quality of life. Although it is known that lymphatic dysfunction and obstruction underlie lymphoedema, the pathogenic mechanism is poorly understood. Smooth muscle cells (SMCs) play pivotal roles in the pathogenesis of various vascular diseases, including atherosclerosis.
DOI: 10.1111/bjd.13482
PubMed: 25319851
Affiliations:
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Le document en format XML
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Ogata</name><affiliation wicri:level="4"><nlm:affiliation>Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 113-8655, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 113-8655</wicri:regionArea><orgName type="university">Université de Tokyo</orgName><placeName><settlement type="city">Tokyo</settlement><region type="province">Région de Kantō</region></placeName></affiliation></author><author><name sortKey="Fujiu, K" sort="Fujiu, K" uniqKey="Fujiu K" first="K" last="Fujiu">K. Fujiu</name><affiliation wicri:level="4"><nlm:affiliation>Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 113-8655, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 113-8655</wicri:regionArea><orgName type="university">Université de Tokyo</orgName><placeName><settlement type="city">Tokyo</settlement><region type="province">Région de Kantō</region></placeName></affiliation></author><author><name sortKey="Koshima, I" sort="Koshima, I" uniqKey="Koshima I" first="I" last="Koshima">I. Koshima</name><affiliation wicri:level="4"><nlm:affiliation>Department of Plastic, Reconstructive and Aesthetic Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 113-8655, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Plastic, Reconstructive and Aesthetic Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 113-8655</wicri:regionArea><orgName type="university">Université de Tokyo</orgName><placeName><settlement type="city">Tokyo</settlement><region type="province">Région de Kantō</region></placeName></affiliation></author><author><name sortKey="Nagai, R" sort="Nagai, R" uniqKey="Nagai R" first="R" last="Nagai">R. 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Manabe</name><affiliation wicri:level="4"><nlm:affiliation>Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 113-8655, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 113-8655</wicri:regionArea><orgName type="university">Université de Tokyo</orgName><placeName><settlement type="city">Tokyo</settlement><region type="province">Région de Kantō</region></placeName></affiliation></author></analytic><series><title level="j">The British journal of dermatology</title><idno type="eISSN">1365-2133</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Actins (metabolism)</term><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Chronic Disease</term><term>Female</term><term>Fibrosis (pathology)</term><term>Humans</term><term>Immunohistochemistry</term><term>Lymphatic Vessels (metabolism)</term><term>Lymphatic Vessels (pathology)</term><term>Lymphedema (metabolism)</term><term>Lymphedema (pathology)</term><term>Male</term><term>Microscopy, Electron, Transmission</term><term>Middle Aged</term><term>Myocytes, Smooth Muscle (metabolism)</term><term>Myocytes, Smooth Muscle (physiology)</term><term>Myosin Heavy Chains (metabolism)</term><term>Phenotype</term><term>Smooth Muscle Myosins (metabolism)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Actines (métabolisme)</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Chaînes lourdes de myosine (métabolisme)</term><term>Femelle</term><term>Fibrose (anatomopathologie)</term><term>Humains</term><term>Immunohistochimie</term><term>Lymphoedème (anatomopathologie)</term><term>Lymphoedème (métabolisme)</term><term>Maladie chronique</term><term>Microscopie électronique à transmission</term><term>Myocytes du muscle lisse (métabolisme)</term><term>Myocytes du muscle lisse (physiologie)</term><term>Myosines du muscle lisse (métabolisme)</term><term>Mâle</term><term>Phénotype</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Vaisseaux lymphatiques (anatomopathologie)</term><term>Vaisseaux lymphatiques (métabolisme)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Actins</term><term>Myosin Heavy Chains</term><term>Smooth Muscle Myosins</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Fibrose</term><term>Lymphoedème</term><term>Vaisseaux lymphatiques</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Lymphatic Vessels</term><term>Lymphedema</term><term>Myocytes, Smooth Muscle</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Actines</term><term>Chaînes lourdes de myosine</term><term>Lymphoedème</term><term>Myocytes du muscle lisse</term><term>Myosines du muscle lisse</term><term>Vaisseaux lymphatiques</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Fibrosis</term><term>Lymphatic Vessels</term><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Myocytes du muscle lisse</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Myocytes, Smooth Muscle</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Chronic Disease</term><term>Female</term><term>Humans</term><term>Immunohistochemistry</term><term>Male</term><term>Microscopy, Electron, Transmission</term><term>Middle Aged</term><term>Phenotype</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Femelle</term><term>Humains</term><term>Immunohistochimie</term><term>Maladie chronique</term><term>Microscopie électronique à transmission</term><term>Mâle</term><term>Phénotype</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Lymphoedema is a debilitating progressive condition that is frequently observed following cancer surgery and severely restricts quality of life. Although it is known that lymphatic dysfunction and obstruction underlie lymphoedema, the pathogenic mechanism is poorly understood. Smooth muscle cells (SMCs) play pivotal roles in the pathogenesis of various vascular diseases, including atherosclerosis.</div></front></TEI><affiliations><list><country><li>Japon</li></country><region><li>Région de Kantō</li></region><settlement><li>Tokyo</li></settlement><orgName><li>Université de Tokyo</li></orgName></list><tree><country name="Japon"><region name="Région de Kantō"><name sortKey="Ogata, F" sort="Ogata, F" uniqKey="Ogata F" first="F" last="Ogata">F. Ogata</name></region><name sortKey="Fujiu, K" sort="Fujiu, K" uniqKey="Fujiu K" first="K" last="Fujiu">K. Fujiu</name><name sortKey="Koshima, I" sort="Koshima, I" uniqKey="Koshima I" first="I" last="Koshima">I. Koshima</name><name sortKey="Manabe, I" sort="Manabe, I" uniqKey="Manabe I" first="I" last="Manabe">I. Manabe</name><name sortKey="Nagai, R" sort="Nagai, R" uniqKey="Nagai R" first="R" last="Nagai">R. Nagai</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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